Acanthosis Cervix – Overview

Here on this page, we will take a look at Acanthosis Cervix and any information around it.

Acanthosis Cervix

Definition / general

  • Benign polypoid lesion composed of a single papillary frond with a central fibrovascular core and mature squamous epithelium

Essential features

  • Composed of a single papillary frond with a central fibrovascular core and mature squamous epithelium without complex arborizing architecture, acanthosis or cellular atypia (koilocytes)

Epidemiology

  • Usually women of reproductive age

Sites

  • Lower genital tract (vagina, vulva, less commonly in cervix)

Etiology

  • Unrelated to HPV infection
  • Predisposing factors unknown

Clinical features

  • Usually asymptomatic but may be associated with burning or dyspareunia

Diagnosis

  • Composed of a single papillary frond with a central fibrovascular core and mature squamous epithelium
  • Lacks the complex arborizing architecture, acanthosis and cellular atypia of koilocytes

Treatment

  • Excision is curative

Gross description

  • May be single or multiple polypoid lesions, usually 5 mm or less

Microscopic (histologic) description

  • Composed of a single papillary frond with a central fibrovascular core and mature hyperplastic squamous epithelium
  • Lacks koilocytic features: complex arborizing architecture, acanthosis, cellular atypia, mitosis

Cytology description

  • Usually negative for abnormal / atypical cells